Product Description of Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid (triflic acid, TfOH) has the formula CF3SO3H and is classified as a superacid, ranking among the strongest acids known.

It features non-oxidizing property, high thermal stability, and resistance to oxidation and reduction. Widely applied in pharmaceuticals, agrochemicals and polymer synthesis, its anhydrous form is especially valuable for fine chemical production.

In pharma manufacturing, it is used to synthesize nucleosides, antibiotics, steroids, proteins and glycosides. Triflic anhydride is highly reactive with water and has significant toxicity.

Product Application of Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid acts as a catalyst for Friedel-Crafts acylation, alkylation and polymerization reactions. It also serves as a solvent for ESR analysis and a strong non-aqueous acid titrant. Combined with trifluoroacetic acid, it is used in solid-phase peptide synthesis. It is acknowledged as one of the strongest monoprotic acids.