Linoleic acid CAS#60-33-3

Linoleic acid CAS#60-33-3

Essential for Human Health: Linoleic acid supports crucial physiological functions, including the synthesis of phospholipids and lipid metabolism, helping maintain overall cellular and metabolic health.


Cholesterol Regulation: It can significantly reduce serum cholesterol levels, making it valuable in preventing and managing hyperlipidemia.


Skin, Hair, and Growth Support: Linoleic acid helps correct growth delays, skin and hair abnormalities, and abnormal serum or adipose tissue composition caused by essential fatty acid deficiency.


Widely Available from Plant Sources: Richly found in plant oils such as soybean, corn, and cottonseed oil, as well as in vegetable oils (excluding palm oil), fish fat, and poultry fat, making it accessible for dietary supplementation.

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Product Description

Product Description of Linoleic acid CAS#60-33-3

As an essential dietary component, linoleic acid is critical for physiological functions such as phospholipid synthesis and lipid metabolism. It effectively lowers serum cholesterol and is a key unsaturated fatty acid for preventing and improving hyperlipidemia.

It also promotes normal growth and development, alleviating growth retardation, skin and hair disorders, and serum or adipose tissue composition imbalances induced by essential fatty acid deficiency. In humans, insufficient intake impairs cell membrane function, while infants may develop eczema due to linoleic acid deficiency.


Product Application of Linoleic acid CAS#60-33-3

Linoleic acid is an essential omega-6 polyunsaturated fatty acid and the most abundant PUFA in common foods. Its main dietary sources include vegetable oils, meat, nuts, seeds and eggs.

In biological experiments, 30 μM linoleic acid can promote the migration of IEC-6 rat intestinal epithelial cells in wound healing assays.

Product Information

Parameters


Melting point-5 °C (lit.)
Boiling point229-230 °C/16 mmHg (lit.)
density0.902 g/mL at 25 °C (lit.)
FEMA3380 | 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%)
refractive indexn20/D 1.466(lit.)
Fp>230 °F
storage temp.Store below +30°C.
solubilityNaOH: soluble1M
pka4.77(at 25℃)
formliquid
colorClear yellow
Odorfaint fatty
biological sourceplant oil (safflower)
Water SolubilityINSOLUBLE
FreezingPoint-5℃
λmax270nm(H2O)(lit.)
SensitiveAir Sensitive
Merck145505
JECFA Number332
BRN1727101
Dielectric constant2.6(0℃)
Stability:Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
Major Applicationflavors and fragrances
Cosmetics Ingredients FunctionsSKIN CONDITIONING - EMOLLIENT
HAIR CONDITIONING
CLEANSING
ANTISTATIC
SKIN CONDITIONING
SURFACTANT - CLEANSING
Cosmetic Ingredient Review (CIR)Linoleic acid (60-33-3)
InChI1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
InChIKeyOYHQOLUKZRVURQ-KQHSAVHASA-N
SMILESOC(CCCCCCC/C=CC/C=CCCCCC)=O
LogP7.05
CAS DataBase Reference60-33-3(CAS DataBase Reference)
NIST Chemistry Reference9,12-Octadecadienoic acid (Z,Z)-(60-33-3)
EPA Substance Registry SystemLinoleic acid (60-33-3)


Safety Information


Hazard CodesXi
Risk Statements36-36/37/38
Safety Statements26-24/25-36-37/39
RIDADRUN1170 - class 3 - PG 2 - Ethanol
WGK Germany1
RTECSRF9990000
F39744
TSCATSCA listed
HS Code29161500
Storage Class10 - Combustible liquids
Hazardous Substances Data60-33-3(Hazardous Substances Data)
ToxicityLD50 oral in mouse: > 50gm/kg


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