Glycvrrhizic acid ammonium salt CAS#53956-04-0

Glycvrrhizic acid ammonium salt CAS#53956-04-0

Extremely Sweet Taste – Ammonium glycyrrhizinate is approximately 200 times sweeter than sucrose, making it a highly effective natural sweetener.


Versatile Food Application – Widely used in food additives for products such as canned meats, seasonings, candies, biscuits, preserved fruits, and beverages.


Glucocorticoid-Like Activity – Exhibits anti-inflammatory, anti-allergic, and membrane-protective effects without the common side effects of corticosteroids.


Hepatic Enzyme Modulation – Strong affinity for hepatic sterol-metabolizing enzymes, inhibiting the inactivation of cortisol and aldosterone, supporting physiological balance.



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Product Description

Product Description of Glycyrrhizic Acid Ammonium Salt CAS#53956-04-0

Ammonium glycyrrhizinate is a highly potent sweetener, approximately 200 times sweeter than sucrose. It is widely used in food additives and can be applied in products such as canned meats, seasonings, candies, biscuits, preserved fruits, and beverages.

Monoammonium glycyrrhizinate exhibits strong affinity for hepatic sterol-metabolizing enzymes, thereby inhibiting the inactivation of cortisol and aldosterone. Upon administration, it provides notable glucocorticoid-like effects, including anti-inflammatory activity, anti-allergic properties, and protection of membrane structures, without causing the typical side effects associated with corticosteroids.


Product Application of Glycyrrhizic Acid Ammonium Salt CAS#53956-04-0

Ammonium glycyrrhizinate is utilized in the synthesis of polyion complex nanocarriers, serving as a template for designing other negatively charged, water-soluble drugs, particularly in combination with anti-inflammatory compounds. Glycyrrhizic acid ammonium salt, derived from licorice flavonoids, also functions as a flavoring and sweetening agent, offering a mild licorice taste with intense, well-rounded sweetness.

It is soluble in water, glycerin, and propylene glycol, and exhibits good thermal stability, although prolonged heating can lead to degradation. It remains stable within a pH range of 3.5–9, but may precipitate below pH 3.5. This compound is suitable for use in beverages, desserts, confectionery products, soups, and salad dressings.


Product Information

Parameters


Melting point>200°C (dec.)
Boiling point768.56°C (rough estimate)
density1.1846 (rough estimate)
FEMA2528 | GLYCYRRHIZIN, AMMONIATED (GLYCYRRHIZA SPP.)
refractive index49 ° (C=1.5, EtOH)
storage temp.2-8°C
solubilitySlightly soluble in water, very slightly soluble in anhydrous ethanol, practically insoluble in acetone. It dissolves in dilute solutions of acids and of alkali hydroxides.
formPowder or Crystals
colorYellow to yellow-green
Odorbland
optical activity[α]20/D +48±4°, c = 1% in ethanol: water (1:1)
BRN3897076
Stability:Hygroscopic
InChIKeyILRKKHJEINIICQ-YDYGGSECSA-N
LogP-0.9
CAS DataBase Reference53956-04-0
EPA Substance Registry Systemalpha.-D-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-D-glucopyranuronosyl-, monoammonium salt (53956-04-0)
RIDADRUN 3077 9 / PGIII
WGK Germany2
RTECSLZ6500000
F46091
HS Code29389090


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